USC vs. Arizona State prediction, odds, line: 2022 college football picks, Week 5 best bets from proven model

The No. 6 USC Trojans return home to face Arizona State on Saturday night at United Airlines Field at the Los Angeles Memorial Coliseum. The Trojans are 4-0 after a close 17-14 road win at Oregon State, while ASU dropped to 1-3, losing at home to No. 12 Utah, 34-13. USC has won five of the last seven meetings, but last year ASU beat the Trojans 31-16 in Tempe.

Kickoff is scheduled for 10:30 p.m. ET. The Trojans are favored by 26 points in the latest USC vs. Arizona State odds from Caesars Sportsbook, and the over/under is set at 61. Before entering any Arizona State vs. USC picks, you’ll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on USC vs. Arizona State and just locked in its picks and CFB predictions. You can head to SportsLine now to see the model’s picks. Here are several college football odds and betting lines for USC vs. Arizona State:

USC vs. Arizona State spread: USC -26USC vs. Arizona State over/under: 61 pointsUSC vs. Arizona State picks: See picks here

Latest Odds:

USC Trojans
-25.5

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USC vs. Arizona State prediction, odds, line: 2022 college football picks, Week 5 best bets from proven model – todaysfan.com